Health TrialsbyHealthPanel

Functional Proteins in Polycystic Ovary Syndrome

ConditionsReproductive AgePCOS (Polycystic Ovary Syndrome)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorJagiellonian University

About this trial

The concentration of functional proteins: kisspeptin, ghrelin, zonulin will be measured and compared in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR), in women with PCOS without IR, and in women without PCOS.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

women aged 18-45 years

Disqualifiers

removal of at least one ovary

treated diabetes of any type

diagnosed and treated metabolic diseases

diagnosed and treated autoimmune diseases

Trial population

women aged 18-45 years managed for menstrual irregularities or for routine check-up

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Measurement of kisspeptin concentration

    Diagnostic test

    Measurement of kisspeptin concentration in fasting venous blood serum

  • Measurement of ghrelin concentration

    Diagnostic test

    Measurement of ghrelin concentration in fasting venous blood serum

  • Measurement of zonulin concentration

    Diagnostic test

    Measurement of zonulin concentration in fasting venous blood serum

Treatment groups

100 Participants
are divided into 3 treatment groups
Group A: Women with polycystic ovary syndrome (PCOS) and insulin resistance (IR)3 interventions
Group B: Women with polycystic ovary syndrome (PCOS) without insulin resistance (IR)3 interventions
Group C: Women without PCOS3 interventions

Trial outcomes

Primary outcomes

1

Measurement and comparison of kisspeptin concentrations expressed in [pg/ml] in all three study groups

Time frame
up to 6 months
2

Measurement and comparison of ghrelin concentrations expressed in [pg/ml] in all three study groups

Time frame
up to 6 months
3

Measurement and comparison of zonulin concentrations expressed in [pg/ml] in all three study groups

Time frame
up to 6 moths

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Jagiellonian University

Lead sponsor

Source ClinicalTrials.gov
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