Gamma-Music Based Intervention for Mild Alzheimer's Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-95
SponsorNortheastern University

About this trial

The study will test and refine a novel brain-stimulation tool using gamma-frequency lights coupled with self-selected music for a gamma-music-based intervention for participants with mild Alzheimer's Disease. Results will yield a gamma-stimulation protocol that reliably influences brain activity (Aim 1), is adaptive, motivating and rewarding to use (Aim 2), and will generate predictions as to who might benefit the most from gamma-MBI (Aim 3). By bridging the gap between neurostimulation and behavioral intervention by combining music therapy with gamma- band neurostimulation, the present project aims to find a sustainable intervention that delays the progression of AD.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Gamma-Music Based Intervention

    Behavioral

    Gamma or Control lights with Music-Based Intervention for 8 week period

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: GammaExperimental treatment 1 intervention
Group B: ControlPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

EEG activity

Gamma-band EEG activity

Time frame
1 hour

Secondary outcomes

1

ADAS-Cog 14

cognitive component of iADRS

Time frame
8 weeks

Other outcomes

Sponsors and contacts

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