The goal of this observational study is to determine the association of gastrointestinal dysfunction through the Gastrointestinal Dysfunction Scale (GIDS) tool and serum concentrations of citrulline and Intestinal fatty-acid binding protein (I-FABP) with primary \[calories received, protein received, parenteral nutrition requirement and 28-day mortality in the intensive care unit (ICU)\] and secondary (development of pneumonia, surgical and cardiovascular complications in the ICU, length of hospital and ICU stay, duration of mechanical ventilation) clinical outcomes in critically ill patients undergoing aortic surgery.
18 years of age or older.
Patients after surgical interventions (elective or urgency) on the aorta with cardiopulmonary bypass.
Invasive mechanical ventilation expected to be required more than 48 hours.
Signed informed consent.
Patients under mechanical ventilation with pre-existing gastrointestinal issues.
Diagnosis of adult congenital heart disease.
Ongoing pregnancy or lactation period.
Simultaneous participation in another clinical study involving experimental therapy.
Adult patients following aortic surgery necessitating invasive mechanical ventilation and an intensive care unit stay of ≥ 48 hours.
Other
Prospective
No intervention
Other interventionNo intervention
Calories delivered daily enterally and/or parenterally
Percentage representation of prescribed calories delivered daily via enteral and/or parenteral routes.
Protein delivered daily enterally and/or parenterally
Daily administration of protein (in grams) through enteral and/or parenteral routes.
Incidence rate of hospital-acquired infections
Infections acquired in the hospital consist of ventilator-associated pneumonia, bloodstream infections, and infections related to urinary catheters
Percentage of repeated operations
This outcome measures the percentage of patients who undergo one or more additional surgical operations related to the same condition after the initial surgery. The percentage is calculated by dividing the number of patients who require a repeat operation by the total number of patients who underwent the initial operation, multiplied by 100 to get the percentage.
ICU readmission rate
Occurrences of patients being readmitted to the ICU from within the hospital.
ICU length of stay
Duration of time (days) in the ICU
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Instituto Nacional de Cardiologia Ignacio Chavez
Lead sponsor
Instituto Nacional de Enfermedades Respiratorias
Collaborator
National Polytechnic Institute, Mexico
Collaborator
