Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of California, San Francisco

About this trial

Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated fat may increase cardiovascular risk. Yet, the literature does not consistently support non-fat dairy as superior to high-fat dairy for reducing cardiometabolic risk. Identifying the comparative health benefits of non-fat versus high-fat dairy milk would be immediately applicable to patients who seek cardiovascular care. In this randomized, case-crossover trial, the investigators seek to efficiently assess the association between high-fat versus non-fat dairy milk consumption and insulin resistance. Utilizing the Eureka Platform, participants will be randomized to limit their liquid milk consumption to whole milk followed by skim milk (or vice versa), measuring the effect of milk fat content on glycemic index and lipid profile.

Eligibility criteria

Qualifiers

Are age ≥18 years

Have a smartphone

Are able to use the Eureka mobile application

Consume, on average, at least one cup of dairy milk daily, at least 5 days per week

Disqualifiers

Non-English speaker

Are lactose intolerant

History of myocardial infarction

History of type I or type II diabetes

Trial design

Treatments tested in this trial

  • Whole Milk-Skim Milk
  • Skim Milk-Whole Milk

Treatment groups

110 Participants
are divided into 2 treatment groups