About this trial
The INDAGA-UK trial is a retrospective, multi-centre observational study in participants with locally advanced and recurrent salivary gland to investigate t its molecular profiling, and to explore new prognostic and druggable markers. We will analyse samples and data from patients diagnosed with salivary gland cancer from 2013 - 2023. Subject and sample identification will occur over a 12-month period. Samples and data will be analysed over the next 12 months prior to study end.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Aged over 18
Histological diagnosis of salivary gland cancer (SGCs)
Availability of archival tissue (acceptable after 2013 up to present)
Ability to give informed consent (if applicable)* for retrieving histological specimen and preform molecular analysis *De-identified archival tissue from deceased patients will be collected as part of the study once REC approval is in place, if the patient was alive when the samples were taken and they are not part of the NHS opt out scheme.
Disqualifiers
Different H&N cancer of other histology
Thyroid cancers
Trial population
Participants with a salivary gland cancer diagnosis
Trial design
Cohort
Retrospective
Treatments tested in this trial
Observation
Other interventionObservational study, no intervention
Treatment groups
Trial outcomes
Primary outcomes
• Description of the molecular and genomic profile of locally advanced and recurrent-metastatic SGCs.
• Description of the molecular and genomic profile of locally advanced and recurrent-metastatic SGCs.
Locations
Sponsors and contacts
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