Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMayo Clinic
About this trial
The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels that supply the heart.
Some mutations may be inherited (passed on) from a parent without an apparent blood vessel problem while others may develop for the first time in the affected person.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Men and women able to give informed consent and complete a 2 page questionnaire
Diagnosis of one or more episodes of spontaneous coronary artery dissection (SCAD)
Biological parent of individual with SCAD
Relative with fibromuscular dysplasia, arterial aneurysm, or arterial dissection
Disqualifiers
Lack of confirmation of SCAD diagnosis
Trial population
Men and women diagnosed with spontaneous coronary artery dissection (SCAD), their biological parents, and relatives with fibromuscular dysplasia, arterial aneurysm, or arterial dissection.
Trial design
Design model
Family-based
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Identification of one or more gene mutation responsible for SCAD
Via GWAS and whole exome sequencing
Time frame
By end of studySponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov