Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Pittsburgh

About this trial

The purposes of this study are:

* to determine if there are specific genetic traits that might explain why patients have developed pulmonary fibrosis; * to determine if specific genetic traits account for differing patterns of inflammation and scar tissue that has formed in the patient's lungs.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18 years of age or older

Diagnosis of pulmonary fibrosis confirmed by physical examination, pulmonary function testing, chest X-ray, and computed tomography (CT) scans.

Adult patients who are seeking treatment at the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease.

Disqualifiers

Under 18 years of age

Non-fibrotic ILD

Trial population

Patient population includes patients who have been diagnosed with a fibrotic interstitial lung disease who have been seen by a Simmons Center Physician.

Trial design

Design model

Cohort

Time perspective

Other

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)

Blood samples will be collected to validate in a large cohort the per- allele associations of prespecified SNPs with IPF case status adjusted for age , sex. smoking, and principal components of ancestry.

Time frame
Sample collection will occur up to 5 years based on the current rate of sample collection.

Secondary outcomes

Other outcomes

Sponsors and contacts

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