Genetics of Uveitis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6+
SponsorThe Cleveland Clinic
About this trial
In order to improve the investigators knowledge about uveitis and the underlying mechanism of disease, the investigators propose collecting blood from patients with uveitis, isolating DNA and sequencing the DNA to identify genetic mutations or associations in these patients.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Any patient above with the diagnosis of uveitis.
Any patient with a diagnosis of infectious uveitis such as toxoplasmosis retinochoroiditis, herpes associated retinitis.
Disqualifiers
Patients who are unable to give consent
Patients in whom an adequated blood sample can not be obtained.
Trial population
Any patient able to sign an informed consent or child of age 6 with parental /guardian consent with the diagnosis of uveitis or infectious uveitis.
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
1,500 Participants
are grouped into 1 trial groupGroup A: Uveitis
Trial outcomes
Primary outcomes
1
Non infectious uveitis
Distinct uveitis conditions will have a polymorphism association or specific mutation.
Time frame
5 yearsSecondary outcomes
1
Infectious uveitis
Infectious uveitis (such as herpes associated uveitis, toxoplasmosis retinochoroiditis) will have specific polymorphisms/mutations in innate immune system genes which predispose the patient to infectious uveitis.
Time frame
5 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov