Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis

ConditionJoint Pain
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorAin Shams University

About this trial

The goal of this clinical trial is to compare the efficiency and efficacy of genicular nerves blockade by chemical phenol neurolysis versus radiofrequency ablation in managing pain in patients suffering from grade IV KOA in term of NRS pain score.

The participants will be evaluated by numeric rating scale and oxford knee score for assessment of pain relief up to 16 weeks.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Grade 4 knee osteoarthritis according to Kellgren-Lawrence radiological classification.

Failure to manage pain with conservative methods.

Disqualifiers

Prior knee replacement

Patients with cardiac pacemakers or implantable cardiac defibrillators.

Septic knee or systemic sepsis.

Allergy to any of the drugs used in the study.

Trial design

Design model

Parallel

Treatments tested in this trial

  • genicular nerve neurolysis

    Procedure/Surgery

    The superior medial genicular nerve (SMGN), superior lateral genicular nerve (SLGN), and inferior medial genicular nerve (IMGN) will be blocked either by phenol neurolysis or radiofrequency ablation

Treatment groups

114 Participants
are divided into 2 treatment groups
Group A: genicular nerve phenol neurolysisExperimental treatment 1 intervention
Group B: genicular nerve radiofrequency ablationExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Numeric rating scale

By an independent physician pain will be recorded using numeric rating scale which is a screening tool used to assess pain severity using a 0 - 10 scale with zero meaning no pain and 10 meaning the worst pain ever.

Time frame
baseline, 2, 4, 8,12 and 16 weeks after the procedure

Secondary outcomes

1

oxford knee score

This score is used to assess both function and pain of the knee on a scale ranging from 0 (worst pain and function) and 48 (best function and no pain) this score will be recorded by an independent physician

Time frame
baseline, 4, 8, 12, 16 weeks after the procedure

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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