German Spondyloarthritis Inception Cohort

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorCharite University, Berlin, Germany

About this trial

The German Spondyloarthritis Inception cohort (GESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in Germany on patients with early SpA including ankylosing spondylitis (AS, also known as radiographic axial spondyloarthritis) and non-radiographic axial SpA. The objectives of GESPIC are to learn about the course of SpA during the very early stage of the disease, to appropriately assess the outcome including radiographic progression of patients after several years of follow-up, to identify outcome predictors, to assess quality of life, function, and costs (direct and indirect costs). GESPIC has been recently expanded to recruit patients with other forms of SpA / conditions associated with SpA: acute anterior uveitis, Crohn's disease as well as with psoriasis / axial psoriatic arthritis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with definite diagnosis of axial spondyloarthritis or juvenile spondyloarthritis.

Patients with definite diagnosis of Crohn's disease.

Patients with definite diagnosis of acute anterior uveitis.

Patients with definite diagnosis of psoriatic arthritis with axial involvement.

Disqualifiers

None

Trial population

Patients included in GESPIC are required to have a definite clinical diagnosis of axial SpA / juvenile SpA (currently only adult patients with radiographic axial SpA = ankylosing spondylitis - AS are recruited) or a definite diagnosis of Crohn's disease or a definite diagnosis of acute anterior uveitis or a definite diagnosis of psoriatic arthritis with axial involvement.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

1,000 Participants
are grouped into 6 trial groups

6

Trial groups

See each trial group below.

Group A: Ankylosing spondylitis
Group B: Non-radiographic axial spondyloarthritis
Group C: Juvenile spondyloarthritis
Group D: Crohn's disease
Group E: Acute anterior uveitis
Group F: Axial psoriatic arthritis

Trial outcomes

This trial has no outcomes listed.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Charite University, Berlin, Germany

Lead sponsor

German Federal Ministry of Education and Research

Collaborator

AbbVie

Collaborator

Amgen

Collaborator

Centocor, Inc.

Collaborator

Schering-Plough

Collaborator

Wyeth is now a wholly owned subsidiary of Pfizer

Collaborator

Berlin Institute of Health

Collaborator

Novartis

Collaborator

UCB Pharma

Collaborator