Gestational Response, Outcomes, and Weight After GLP-1 Use
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorUniversity of Kansas Medical Center
About this trial
The goal of this observational study is to learn if using GLP-1RA medications for weight loss before pregnancy influences gestational weight gain and pregnancy outcomes. The main aims of the study are to:
* Compare gestational weight gain between women with preconception GLP-1RA exposure and those without exposure. * Compare obstetrical outcomes between women with preconception GLP-1RA exposure and those without exposure.
Researchers will compare pregnant women with a history of GLP-1RA use to pregnant women who have not used a GLP-1RA to compare differences.
Participants will be asked to complete questionnaires at multiple timepoints during and after pregnancy that ask questions about medication history, thoughts and feelings around food, etc.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Adult women
Less than or equal to 20 weeks gestation at first visit
English speaking
Disqualifiers
<18 years at time of initial visit
Type 2 diabetes
History of bariatric surgery
Multiple gestation
Trial population
Pregnant women being seen at The University of Kansas Health System for an initial prenatal visit.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
400 Participants
are grouped into 2 trial groupsGroup A: GLP-1RA users
Group B: GLP-1RA nonusers
Trial outcomes
Primary outcomes
1
Gestational weight gain
Total gestational weight gain, calculated from clinical weight measurements recorded in the electronic medical record and compared between participants with preconception GLP-1RA exposure and those without exposure.
Time frame
From the start of pregnancy to delivery.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov