The study aims to evaluate the effect of ginger supplementation on inflammatory cytokines and markers of oxidative stress in patients with Coronary Artery Disease (CAD). A longitudinal double-blind randomized clinical trial will be carried out, involving CAD participants for two months.
Both sexes
Over 18 years of age;
Diagnosed with Coronary Artery Disease: confirmed by coronary angiography, coronary computed tomography angiography, or functional testing with ischemic load);
Participants who are asymptomatic or have angina limited to functional class III will be considered;
Unstable Coronary Artery Disease;
Pre-operative coronary artery bypass grafting or awaiting elective angioplasty;
Unstable angina;
NYHA functional class III or higher;
Parallel
Ginger
Dietary supplementParticipants will receive 2 capsules per day, providing the ginger extract daily, at a dosage of 500mg.
Placebo
Dietary supplementThe placebo group will receive the same amount of 500mg placebo, at the same time, containing corn starch.
Change of inflammatory status in the participants
Get blood samples to evaluate the supplementation effects in inflammatory biomarkers: interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), C-reactive protein (CRP).
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Universidade Federal Fluminense
Lead sponsor
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Collaborator
Rio de Janeiro State Research Supporting Foundation (FAPERJ)
Collaborator
This trial is not recruiting at the moment. You can still explore other options:
