Glucose-Level During Endurance Exercise
ConditionGlucose Metabolism
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Ulm
About this trial
As part of the mandatory annual assessment of physical fitness, soldiers are required to complete a standardized military march. A total of 100 healthy volunteer participants will be recruited from soldiers serving at the Bundeswehr Hospital Ulm. During this march, physiological and metabolic parameters will be assessed.
At baseline, anthropometric data and information on medical history, lifestyle, and fitness status will be collected, including a validated questionnaire on physical activity. Blood and urine samples will be obtained to determine routine laboratory and metabolic parameters, and body composition will be assessed using bioelectrical impedance analysis. In addition, selected sensors will be applied to continuously record physiological data.
Participants will then complete a 6 km march carrying 15 kg of equipment. After completion of the march, sensors will be removed and additional blood and urine samples will be collected to evaluate metabolic responses to physical exertion, including catecholamine levels.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
BMI between 18.5 and 30 kg/m²
Disqualifiers
Pregnancy or lactation
cardiovascular disease
vegan diet
drug or alcohol abuse
Trial population
healthy volunteer participants recruited from soldiers serving at the Bundeswehr Hospital Ulm
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Standardized military march
Other intervention6 km march carrying 15 kg of equipment. The march will be conducted in uniform in accordance with central military regulations. Participants will be equipped with a continuous glucose monitor an electrocardiography wearable during the march. Before and after the march blood and urine samples will be obtained.
Treatment groups
100 Participants
are divided into 1 treatment groupGroup A: Soldiers1 intervention
Trial outcomes
Primary outcomes
1
Glucose dynamics during exercise
Interstitial glucose responses during the standardized endurance exercise (6 kilometer march with 15 kilogram load) measured via continuous glucose monitoring.
Time frame
1 hour2
Sympathetic nervous system activation (catecholamines)
Activation of the sympathetic nervous system during a standardized endurance exercise measured via changes in catecholamine levels.
Time frame
Baseline, immediately after the march (approximately 1 hour after baseline)3
Correlation between sympathetic activation (catecholamines) and glucose dynamics during endurance exercise
Correlation between sympathetic nervous system activation measured via catecholamine levels and glucose responses during a standardized endurance exercise (6 kilometer march with 15 kilogram load).
Time frame
Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline)4
Heart rate variability
Heat rate variability during a standardized endurance exercise measured via electrocardiography.
Time frame
Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline)Secondary outcomes
1
Training status
Individual fitness level assessed via the Movement and Sport Activity questionnaire (sport and physical activity based on reported frequency and duration of activities and provides estimates of activity in minutes per week or MET-hours per week)
Time frame
Baseline2
Correlation between training status and glucose dynamics during endurance exercise
Correlation between training status and glucose responses during the standardized endurance exercise.
Time frame
Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline)3
Body composition
Muscle mass in kilogram assessed by bioelectrical impedance analysis.
Time frame
Baseline.4
Correlation between body composition and glucose dynamics during exercise.
Correlation between muscle mass and glucose responses during the standardized endurance exercise.
Time frame
Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline)Other outcomes
1
Sex differences in correlation between sympathetic activation (catecholamines) and glucose dynamics during endurance exercise
Comparison of sympathetic activation measured via catecholamines and glucose dynamics during endurance exercise between sexes.
Time frame
Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline)2
Sex differences in the correlation between heart rate variability and glucose dynamics during endurance exercise
Comparison of the correlation between heart rate variability and glucose responses during a standardized endurance exercise (6 kilometer march with 15 kilogram load) between sexes.
Time frame
Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline)3
Sex differences in the correlation of training status with glucose dynamics during endurance exercise
Comparison of correlation of individual fitness level and glucose responses during the standardized endurance exercise between sexes.
Time frame
Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline)4
Sex differences in the influence of body composition on glucose dynamics during exercise
Comparison of the influence of body composition on glucose dynamics during exercise between sexes.
Time frame
Baseline, during the 1 hour-march, immediately after the march (approximately 1 hour after baseline)Sponsors and contacts
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Source ClinicalTrials.gov