Glycolytic Phenotype (vLapeak) and Magnitude of Skeletal Muscle Hypertrophy After Resistance Training

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-39
SponsorTechnical University of Munich

About this trial

The HyperLa study investigates whether a person's "glycolyticness"-the efficiency with which their body uses glycolysis for energy-can predict how much their muscles will grow (hypertrophy) in response to resistance training. Participants will undergo a specialized "vLapeak" test, which measures the maximal rate of lactate accumulation during a 10-second all-out cycling sprint, to determine their individual glycolytic power. Following this initial assessment, participants will complete eight weeks of standardized, twice-weekly resistance training focused on the lower body. The study aims to determine if individuals with higher initial vLapeak values experience greater increases in muscle size compared to those with lower values. This research may help explain why people respond differently to exercise and support the development of personalized training programs.

Eligibility criteria

Qualifiers

Body Mass Index (BMI) between 20-29 kg/m2

No structured resistance training performed in the last twelve months.

Maximum of four sessions per week of recreational or low-to-moderate aerobic endurance activity.

No history of competitive strength or physique sports.

Disqualifiers

Diagnosed cardiovascular, pulmonary, metabolic, neuromuscular, or orthopaedic disease that contraindicates exercise.

Positive response to any question on the PAR-Q 2025 questionnaire.

Current use of anabolic steroids, creatine, or other substances known to strongly influence muscle hypertrophy.

Regular engagement in shift work.

Trial design

Treatments tested in this trial

  • Hypertrophy-focused Resistance Training

Treatment groups

120 Participants
are divided into 1 treatment group

Sponsors and collaborators

Technical University of Munich

Lead sponsor

Chemnitz University of Technology

Collaborator

DLR German Aerospace Center

Collaborator

University of Jyvaskyla

Collaborator

University of Limerick

Collaborator

IST University of Applied Sciences Düsseldorf

Collaborator

Institute for Applied Training Science (IAT/FES e.V.)

Collaborator