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Gradual Versus Intermittent Release of Tourniquet Effect on MAP in Hypertensive Patients Undergoing Upper Limb Orthopedic Surgeries

ConditionHemodynamics
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorKasr El Aini Hospital

About this trial

In this clinical trial, the authors will compare two tourniquet deflation techniques and their clinical implications on hemodynamics and acid base parameters in hypertensive orthopedic patients undergoing upper limb surgeries under general anesthesia.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Hypertensive patients (controlled on medical treatment more than three months)

Patients scheduled for upper limb orthopedic surgeries using a tourniquet for at least 30 min.

BMI from 18.5 to 29.9

Disqualifiers

Patient refusal

ASA physical status > II

Multiple orthopedic surgeries

Emergency surgeries

Trial design

Design model

Parallel

Treatments tested in this trial

  • Tourniquet deflation

    Device

    Tourniquet deflation technique

Treatment groups

68 Participants
are divided into 2 treatment groups
Group A: G groupExperimental treatment 1 intervention
Group B: I groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Mean Arterial Pressure

The decrease in MAP (more than 25% compared to baseline) 5 minues after deflation.

Time frame
5 minutes

Secondary outcomes

1

Acid base status

Acid base status

Time frame
5 minutes
2

Lactate

Lactate level

Time frame
30 minutes
3

Potassium level

Potassium level

Time frame
30 minutes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Kasr El Aini Hospital

Lead sponsor

Source ClinicalTrials.gov
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