About this trial
The Harnessing Optimism and Perseverance in the Face of Long COVID (HOPE-LC) program, created by Drs. Eric Watson and Amelia Hicks, is a group therapy model designed to foster resilience, adjustment, and coping skills for those living with chronic Long COVID. HOPE-LC\~Español provides a culturally and linguistically adapted version for Spanish-speaking individuals in Queens, developed with input from Spanish-speaking clinicians, Long COVID experts, and people with lived experience. Partnering with H+H/Elmhurst and H+H/Queens, the project aims to recruit 25 participants and evaluate program feasibility and preliminary efficacy.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18 years or older.
Speaks and understands Spanish at a level that allows active participation in group-based study procedures.
Self-reported history of Long COVID/post-COVID condition of any severity or duration, including ongoing emotional or cognitive symptoms affecting daily functioning or a medical professional has diagnosed you with a Long COVID/post-COVID condition of any severity or duration, including ongoing emotional or cognitive symptoms.
Ability to participate in group sessions either in-person or via telehealth (Zoom).
Disqualifiers
Presence of severe psychiatric conditions that would preclude participation in group therapy (e.g., active psychosis, suicidal intent requiring immediate intervention).
Inability to communicate in Spanish sufficiently to engage meaningfully in group sessions.
Cognitive or physical impairments prevent participation in group sessions or completion of surveys, without available accommodations.
Concurrent participation in another conflicting interventional trial targeting Long COVID symptoms.
Trial design
Single group
Treatments tested in this trial
HOPE-LC~Espanol
Behavioral12-week online group therapy program grounded in principles of Acceptance and Commitment Therapy and tailored specifically to living with Long COVID as a chronic condition. HOPE-LC provides community and hope; fostering resilience, adjustment, and critical coping strategies in the face of this debilitating chronic condition.
Treatment groups
Trial outcomes
Primary outcomes
Recruitment rate
Number of eligible participants screened and enrolled by referral source
Retention rate
Number of participants completing the intervention (defined as attending at least 8 of 12 sessions)
Number of sessions participants attended
Feasibility measured via participant attendance
Number of completed surveys
Feasibility measured via number of surveys completed from participant follow-up and study procedures.
Secondary outcomes
DePaul Symptom Questionnaire
The DePaul Symptom Questionnaire (DSQ) is a validated tool to assess symptoms, frequency and severity of various symptoms of fatigue and other neurological impairment. Total score range 0-100, with higher scores indicating greater symptom severity and functional impairment.
Brief Illness Perception Questionnaire (BIPQ)
The BIPQ assesses cognitive and emotional representations of illness in 8 items + 1 open-ended causal item. Total score range is 0-80, higher scores mean a more negative perception of illness.
Valued Based Living Questionnaire (VLQ)
Assesses alignment between personal values and daily actions. Two ratings per domain: (1) Importance (1-10) and (2) Consistency with actions (1-10). Total score range is between 4-40. Higher consistency scores reflect greater valued living (better outcome); lower scores reflect minimal valued living (worse outcome).
Modified COVID-19 Yorkshire Rehabilitation Scale (C19-YRSm)
The C19-YRSm is a 17-item self-report scale designed to assess the impact of post-COVID symptoms. Items are rated on a scale from 0 (none of this symptom) to 3 (extremely severe level or impact). The scale includes four subscales: Symptom Severity (Questions 1-10; score range: 0-30) Functional Disability (Questions 11-15; score range: 0-15) Other Symptoms (Question 16; score range: 0-25) Overall Health (Question 17; score range: 0-10) Full scale from 0-80. Higher scores indicate greater symptom severity and functional impairment.
Sponsors and contacts
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