The goal of the HARMONIC-RT study is to evaluate late health and social outcomes of contemporary techniques of external beam radiotherapy in paediatric patients, based on the setting-up of a European, long-term registry complemented by a biobank.
First external beam radiation therapy (EBRT) started in 2000 or after for management of a first primary neoplasm
Age under 22 years at the time of first EBRT initiation
Radiation treatment plan (first EBRT) stored in DICOM format
Usual residency in the country of EBRT to enable a long-term follow-up
Patients with poor prognosis (e.g. diffuse pontine glioma or high grade glioma) at first EBRT initiation
Prior external or internal radiation therapy
Patients who refused to participate in the study
Scheduled first EBRT for management of a first primary neoplasm
Institut National de la Santé Et de la Recherche Médicale, France
Lead sponsor
Barcelona Institute for Global Health
Collaborator
The West German Proton Therapy Centre, Essen
Collaborator
Gustave Roussy, Cancer Campus, Grand Paris
Collaborator
Centre Francois Baclesse
Collaborator
KU Leuven
Collaborator
University of Aarhus
Collaborator
Princess Maxima Center for Pediatric Oncology
Collaborator
University Medical Center Groningen
Collaborator
Stockholm University
Collaborator
National Research Council, Institute of Clinical Physiology, Italy
Collaborator
University of Zurich
Collaborator
Commissariat A L'energie Atomique
Collaborator
Luxembourg Institute of Science and Technology
Collaborator
University Hospital, Essen
Collaborator
Aarhus University Hospital
Collaborator