Heart Analysis in GATED-PET in Patients Having a Gallium-68-DOTATOC PET/CT Exam for Oncology Indication

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentral Hospital, Nancy, France

About this trial

Gallium-68-DOTATOC binds primarily with high affinity to somatostatin subtype 2 (SSTR2) receptors and these somatostatin receptors are also overexpressed on inflammation cells when activated.

The hypothesis is that the GATED mode on a Gallium-68-DOTATOC cardiac recording would be able to highlight abnormalities that could be correlated with the age of the patients and their cardiovascular risk factors.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥ 18 years old.

Having read and understood the information document.

Affiliated to a social security scheme.

Disqualifiers

Hypersensitivity during previous use of 68Ga-DOTATOC

Impossibility of performing a PET-CT (patient agitated, confused, etc.).

History of heart disease,

Severe arrhythmia that does not allow the PET synchronized with the ECG

Trial design

Design model

Single group

Treatments tested in this trial

  • Cardiac ECG-gated PET imaging will added

    Other intervention

    Blood sample will be used to measure troponin, BNP and CRP . After 68Ga-DOTATOC PET/CT whole body recording, a cardiac ECG-gated PET imaging will added

Treatment groups

99 Participants
are divided into 1 treatment group
Group A: PatientsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Relationship between the captation of radiotracer and the cardiovascular disease

Measurement of myocardial activity

Time frame
1 day

Secondary outcomes

1

Relationship between the captation of radiotracer and the troponin value

Correlation between the myocardial activity and the troponin value

Time frame
1 day

Other outcomes

Sponsors and contacts

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