Study aim is comparison of heart failire with preserved ejection fraction (HFpEF) detection rate in patients with Сhronic Obstructive Pulmonary Disease (COPD) and the clinical course and prognosis in patients with COPD depending on HFpEF presence.
Verified diagnosis of COPD;
Patients hospitalized with COPD;
Citizenship of the Russian Federation;
Patients aged 50 to 70 years;
Lack of Russian Federaion citizenship;
Patient's refusal to participate in the study;
Any chronic diseases, other than COPD, that affect the prognosis, in the acute and/or decompensated stage;
Mental disorders.
Generic russian population
Cohort
Other
Echocardiography
Diagnostic testTransthoracic echocardiography at rest: with determination of epicardial fat tissue thickness, epicardial adipose tissue thickness (EAT), E/e', interventricular septum thickness, left ventricular posterior wall thickness, and end-diastolic dimension
Spirometry
Diagnostic testSpirometry is the most common of the pulmonary function tests, which measures the lung capacity and airway patency (volume and speed of air) during quiet and forced breathing.
Body plethysmography
Diagnostic testBody plethysmography is a non-invasive lung function test performed in a sealed booth (body box) that measures total lung volume, functional residual capacity, and airway resistance by using Boyle's Law to track pressure and volume changes as a patient breathes, providing crucial data for diagnosing conditions like COPD and asthma, and differentiating them from other lung disorders
6-Minute Walk Test (6MWT)
Diagnostic testThe 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity
laboratory biomarker analysis
Diagnostic testRoutine and special laboratory tests
Primary composite endpoin
Primary composite endpoint: all-cause death, rehospitalizations, major adverse cardiovascular events (MACE)
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National Medical Research Center for Therapy and Preventive Medicine
Lead sponsor
Kazan State Medical University
Collaborator
