HeartShare is a comprehensive study of heart failure, a common and serious medical condition which occurs when the heart is unable to keep up with the demands of the body, resulting in shortness of breath, fluid retention, and fatigue. HeartShare aims to better classify heart failure into subtypes to help develop more personalized treatments for patients, with the hope that this will improve the lives of heart failure patients. To do this, HeartShare is bringing together a large amount of data (including images, such as heart ultrasounds and MRIs and molecular data from the blood, such as genetics) from previously conducted studies and electronic health records, and is gathering new data through participants enrolled in the HeartShare Deep Phenotyping Study.
Age ≥30 years.
Prior diagnosis of HF in the EHR (any left ventricular ejection fraction).
Age ≥30 years.
No known prior diagnosis of HF or use of loop diuretics.
For non-HF group: any prior known left ventricular ejection fraction <50%.
Prior history of solid organ transplantation.
Prior history of mechanical circulatory support.
Prior history of non-cardiac cirrhosis.
Adults over 30 years of age.
Cohort
Prospective
Not listed
Number of participants with Heart Failure with Preserved Ejection Fraction (HFpEF)
Click on the lead sponsor to view all of their trials.
Northwestern University
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Massachusetts General Hospital
Collaborator
Brigham and Women's Hospital
Collaborator
Mayo Clinic
Collaborator
University of California, Davis
Collaborator
Wake Forest University Health Sciences
Collaborator
University of Pennsylvania
Collaborator
