Health TrialsbyHealthPanel

Heat thErapy And mobiLity in COVID-19 Survivors

ConditionLong COVID
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-90
SponsorUniversity of Nebraska

About this trial

Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and disabilities. Although exercise intervention is a common strategy to restore functional capacity, it may not be feasible or enticing to many people with PASC. This clinical trial seeks to establish the tolerability and efficacy of at home lower-body heat therapy for improving functional capacity along with metabolic and vascular health in late-middle aged and older adults with PASC, also known as "long COVID".

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Between the ages of 50 and 90 years

Free from orthopedic limitations that would prohibit performing leg exercise

BMI < 40 kg/m2 and weigh < 400lbs

Previously contracted Covid-19 and have persistent symptoms such as a fatigue or decline in physical function, for at least 2 months following SARS-CoV-2 infection

Disqualifiers

Unable to give written informed consent

Women who are pregnant, breastfeeding, or likely to become pregnant within the next 6 months

Claustrophobia

Orthopedic limitations that would prohibit them from walking

Trial design

Design model

Parallel

Treatments tested in this trial

  • Heat therapy

    Behavioral

    At home lower body heat therapy

  • Sham Control

    Behavioral

    Sham Thermoneutral

  • Walking

    Behavioral

    Walking intervention

Treatment groups

99 Participants
are divided into 3 treatment groups
Group A: Heat TherapyExperimental treatment 1 intervention
Group B: Control TherapySham comparator 1 intervention
Group C: Walking Intervention Using Wearable TechnologyActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

6 min walking distance

Distance covered during 6 min of walking

Time frame
8 weeks
2

Short Physical Performance Battery Test

Test of physical functional capacity

Time frame
8 weeks
3

Arterial stiffness

Pulse Wave velocity

Time frame
8 weeks

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Nebraska

Lead sponsor

National Institute on Aging (NIA)

Collaborator

Source ClinicalTrials.gov
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