Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control Subjects
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorMayo Clinic
About this trial
This study evaluates hematopoiesis to determine how MBL/CLL affected bone marrow responds to fight off infections in the body.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Subjects in the CLL cohort who are eligible for these studies will have a clinically established diagnosis of CLL as assessed by flow cytometry and will include subjects who
Remain untreated
Are currently being treated
Who have already been treated
Disqualifiers
Anyone under 40
Healthy control subjects must not have a diagnosis of CLL or MBL
Trial population
Patients with MBL, patients with CLL ,and healthy subjects recruited through Mayo Clinic.
Trial design
Design model
Case-control
Time perspective
Cross-sectional
Treatments tested in this trial
Non-Interventional Study
Other interventionNon-interventional study
Treatment groups
50 Participants
are divided into 1 treatment groupGroup A: Observational1 intervention
Trial outcomes
Primary outcomes
1
Effects of MBL on bone marrow function
Samples collected from healthy participants and participants with MBL will be compared for differences in bone marrow function (i.e., ability to fight off infection). Results will be descriptive. With participant permission, samples will be stored for future research use.
Time frame
Baseline2
Effects of CLL on bone marrow function
Samples collected from healthy participants and participants with CLL will be compared for differences in bone marrow function (i.e., ability to fight off infection). Results will be descriptive. With participant permission, samples will be stored for future research use.
Time frame
BaselineSponsors and contacts
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Source ClinicalTrials.gov