Hemodynamic Venous Congestion Ultrasound (VExUS) by ICU Nurses in Sepsis Patients.
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorRegion Örebro County
About this trial
Sepsis is a serious condition where the body's immune response to infection overreacts, leading to organ damage and death. Venous congestion, a buildup of blood in the veins, can occur in sepsis and contribute to organ injury. VExUS (Venous Excess Ultrasound Score) is an ultrasound method that can detect congestion early. This study examines whether ICU nurses, after training, can perform VExUS reliably, explores their experiences, and investigates links between VExUS findings and clinical outcomes.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients with suspected or verified sepsis according to the Sepsis 3 criteria (suspected or confirmed infection), ≥qSOFA (systolic blood pressure < 90 mmHg, GCS ≤ 13, respiratory rate ≥ 22 per minute) or rise in SOFA score ≥ 2 points and admitted to the ICU.
≥18 years of age.
Disqualifiers
Patients with preexisting liver cirrhosis.
Pregnancy.
Trial population
Intensive care nurses with a specialist degree in intensive care and intensive care patients with sepsis.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Education in performing hemodynamic diagnostic ultrasound of venous congestion
BehavioralEducational program in performing hemodynamic diagnostic ultrasound of venous congestion
Hemodynamic diagnostic ultrasound of venous congestion
Diagnostic testHemodynamic diagnostic ultrasound of venous congestion
Treatment groups
46 Participants
are divided into 2 treatment groupsGroup A: Intensive care nurse1 intervention
Group B: Intensive care patients1 intervention
Trial outcomes
Primary outcomes
1
Intensive care nurses' VExUS performance
Intensive care nurses' performance, regarding ultrasound image quality and assessment of ultrasound images according to VExUS protocol, evaluated by two experts.
Time frame
two yearsSecondary outcomes
1
Intra-rater VExUS reliability
Agreement of assessments of prior collected ultrasound images, according to VExUS protocol, performed by the same intensive care nurse.
Time frame
two years2
Inter-rater VExUS reliability
Agreement of assessments of prior collected ultrasound images according to VExUS protocol performed by different intensive care nurses.
Time frame
two years3
Inter-rater VExUS image agreement
Agreement of the ability to obtain ultrasound images according to VExUS protocol performed on the same intensive care patients by different intensive care nurses, in temporal proximity.
Time frame
two years4
Venous congestion measured by VExUS and fluid status
Association of presence of venous congestion assessed by VExUS over time in septic intensive care patients and daily measures used to monitor fluid status, such as daily weight, daily fluid balance and cumulative fluid balance.
Time frame
two yearsLocations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Region Örebro County
Lead sponsor
Örebro University, Sweden
Collaborator
Region Östergötland
Collaborator
Dalarna County Council, Sweden
Collaborator
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: