Patients treated with hemodialysis (HD) bear increased risk of cardiovascular events, which results in high morbidity and mortality among this cohort of patients. Intradialytic hypotension (IDH), which is an independent risk factor for mortality, occurs in up to 20% of hemodialysis session and may lead to myocardial stunning and cerebral ischemia resulting in increased white matter lesions, gastrointestinal ischemia and shunt vessel thrombosis. Due to the deleterious effects of IDH during HD, preventive measurements such as limiting interdialytic weight gain are recommended, but frequently fluid and salt restriction are not adhered to, thus increasing dialysis time or frequency of treatments is a common strategy in those patients.
Written consent of the participant after being informed
At least 18 years of age
End stage kidney disease patient undergoing hemodialysis
Dry weight stable for a minimum of one month
No informed consent was obtained
Patients with a pacemaker or implanted medical device that prevents compliance with study regulations
Patients treated with hemodiafiltration
Patients treated with medium cut-off membranes (Theranova, Baxter)
Crossover
isolated Ultrafiltration (iso-UF)
Procedure/Surgeryisolated Ultrafiltration
Total peripheral resistance index (TPRI)
Absolute change of TPRI (expressed as dyn\*sec/cm\*m2) in each individual session from baseline to the nadir.
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