Hepatocarcinoma Recurrence on the Liver Study - Part2
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Milano Bicocca
About this trial
Rationale for the trial. To evaluate the impact of surgery on hepatocarcinoma recurrence. Thus, to evaluate the impact of different clinical, radiological, histopathological variables on recurrence after surgical treatment. The nature of this study will allow to observe, over time, the distribution of the considered collection variables, allowing a strictly observational monitoring of possible associations able to suggest models or interpretations, which can then be the basis for the construction of prospective and randomized studies.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
No age limit.
Hepatocarcinoma diagnosis confirmed at histological specimen
Every single patients with first HCC diagnosis or with a recurrence/persistence disease evaluated and treated with surgery at the participating center.
the assessment for patient enrollment must have been performed starting from 02/02/2019.
Disqualifiers
Surgery as a downstaging therapy for transplant
Patients treated with surgery in case of not-curative intent (palliation, best supportive care, etc).
Histopathological specimen of combined liver primary neoplasms (e.g. "hepatocholangiocarcinoma'').
Patients with other tumors in the previous past.
Trial population
All consecutive patients treated by surgery for HCC
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
liver resection
Other interventionall type of liver surgical procedures
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Disease-free-Survival
Disease Free Survival: the time between surgery and event of recurrence or death measured in months. If no event, patients will be censored at the last available follow-up date.
Time frame
15 years of follow-up2
Overall Survival
The time from surgery to death measured in months. If no event, patients will be censored at the last available follow-up.
Time frame
15 years of follow-upSecondary outcomes
1
Localization of the recurrence
Presence of relapse disease on the surgical cut surface rather than at distance
Time frame
15 years of follow-up2
Number of redo-surgery
Number of patients who experienced a recurrence after first surgery and has been submitted to a redo-surgery procedure
Time frame
15 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: