HFNC During Bronchoscopy in COPD Patients
ConditionCOPD
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe First Affiliated Hospital of Guangzhou Medical University
About this trial
Bronchoscopy diagnosis and treatment is highly irritating, and the effect of local topical anesthesia is poor; the airway is shared; and COPD patients have low oxygen reserves due to impaired lung function. At present, clinical anesthesia generally uses nasal cannula for oxygen inhalation. If the anesthesia is too shallow, it may cause airway spasm, and if the anesthesia is too deep, it will inhibit breathing and lead to hypoxia. Hypoxemia has been reported in 66% of COPD patients undergoing sedation for bronchoscopy. Therefore, solving hypoxia is the biggest problem in anesthesia for bronchoscopy diagnosis and treatment.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
COPD ,（ASA）Ⅰ ～ Ⅲ
Disqualifiers
Contraindications to bronchoscopy or anesthesia, Nosebleeds
Trial design
Design model
Parallel
Treatments tested in this trial
group N used traditional nasal cannula for oxygen inhalation
Other intervention1000 COPD patients who underwent bronchoscopy were randomly divided into 2 groups in a 1:1 ratio.Nasal high-flow oxygen therapy group（group N） and nasal cannula oxygen inhalation group(group HFNC）.The N group used traditional nasal cannula for oxygen inhalation, and the HFNC group used nasal high-flow oxygen inhalation.
Group HFNC used nasal high-flow oxygen inhalation.
Other intervention1000 COPD patients who underwent bronchoscopy were randomly divided into 2 groups in a 1:1 ratio.Nasal high-flow oxygen therapy group（group N） and nasal cannula oxygen inhalation group(group HFNC）.The N group used traditional nasal cannula for oxygen inhalation, and the HFNC group used nasal high-flow oxygen inhalation.
Treatment groups
1,000 Participants
are divided into 2 treatment groupsGroup A: Group NOther 1 intervention
Group B: Group HFNCExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
pulse oximetry
Blood oxygen saturation during anesthesia, record the duration and number of times below 90%
Time frame
The entire anesthesia period during bronchoscopyLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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