HFNC for Postoperative Atelectasis After Laparoscopic Surgery
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBursa Yuksek Ihtisas Training and Research Hospital
About this trial
Pneumoperitoneum and Trendelenburg positioning during laparoscopic surgery promote atelectasis development, which has been reported in up to 90% of patients under general anesthesia and increases the risk of postoperative pulmonary complications. High-flow nasal cannula (HFNC) oxygen therapy may reduce post-extubation atelectasis through alveolar recruitment. This prospective observational cohort study aims to evaluate the role of HFNC in postoperative atelectasis monitored by lung ultrasonography (LUS) in patients undergoing elective laparoscopic surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patients aged 18 years and older
Patients scheduled for elective laparoscopic surgery (general surgery, urology, gynecology)
Patients undergoing mechanical ventilation under general anesthesia
ASA physical status I-III
Disqualifiers
Severe or uncontrolled chronic obstructive pulmonary disease, asthma, or other chronic pulmonary diseases
Patients with atelectasis or pleural effusion detected on preoperative lung ultrasonography
Patients requiring intraoperative recruitment maneuver
ASA physical status IV or above
Trial population
Adult patients aged 18-75 years scheduled for elective laparoscopic surgery (general surgery, urology, and gynecology) under general anesthesia.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
High-Flow Nasal Cannula (HFNC)
Other interventionHFNC Group
Conventional Oxygen Therapy
Other interventionStandard oxygen therapy administered via face mask or nasal cannula after extubation following elective laparoscopic surgery.
Treatment groups
90 Participants
are divided into 2 treatment groupsGroup A: HFNC Group1 intervention
Group B: Control Group1 intervention
Trial outcomes
Primary outcomes
1
Total Lung Ultrasonography Score (LUS Score)
Total lung ultrasonography score assessed using the Monastesse modified LUS scoring system. Each hemithorax is divided into 6 segments along parasternal, anterior axillary, and posterior axillary lines, evaluating a total of 12 thoracic regions with a total score ranging from 0 to 36 points. Scores are compared between HFNC and conventional oxygen therapy groups.
Time frame
T0: preoperative; T1: 5th minute after extubation; T2: 30th minute in the recovery unit; T3: discharge from the recovery unitSecondary outcomes
1
Incidence of Significant Atelectasis
Proportion of patients with at least one lung region scoring ≥2 on the LUS scoring system (coalescing B-lines/irregular pleura or consolidation \>1×2cm) at each time point.
Time frame
T0: preoperative; T1: 5th minute after extubation; T2: 30th minute in the recovery unit; T3: discharge from the recovery unit2
Minimum SpO₂ in the Post-Anesthesia Care Unit (PACU)
Minimum oxygen saturation recorded during the entire post-anesthesia care unit stay.
Time frame
From extubation to PACU discharge, up to 2 hours3
Incidence of Hypoxemia
Proportion of patients with SpO₂ below 95% during the post-anesthesia care unit stay.
Time frame
From extubation to PACU discharge, up to 2 hours4
Incidence of Severe Hypoxemia
Proportion of patients with SpO₂ below 90% during the post-anesthesia care unit stay.
Time frame
From extubation to PACU discharge, up to 2 hoursLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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