HFNC in Management of Bronchiectasis Exacerbation

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorAssiut University

About this trial

Patients with Bronchiectasis experience exacerbations with hypercapnic respiratory failure associated with an increased respiratory workload that may require intensive care unit (ICU) admission due to the inability of the respiratory muscles to compensate for increased demand. These exacerbations are frequently treated with noninvasive ventilation (NIV).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients will be eligible for enrolment if diagnosed with bronchiectasis and admitted to the respiratory intensive care unit (RICU), requiring ventilator support without invasive mechanical ventilation.

Disqualifiers

Age: less than 18 years. Patients with post-arrest encephalopathy. Patient with the previous tracheotomy. Patients who received invasive ventilatory support. Patients with end-organ failure.

Trial population

Patients will be eligible for enrolment if diagnosed with bronchiectasis and admitted to the respiratory intensive care unit (RICU), requiring ventilator support without invasive mechanical ventilation.

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

  • bi-level ventillation

    Drug

    non-invasive mechanical ventilation

Treatment groups

20 Participants
are divided into 2 treatment groups
Group A: Patient need NIV ventillation1 intervention
Group B: patient need HFNC0 interventions

Trial outcomes

Primary outcomes

1

Assessment of efficacy and patient compliance of high flow nasal canula system in comparison to Noninvasive mechanical ventilation in management of acute exacerbation of Bronchiectasis

The duration of ICU admission days and the patient compliance to both devices will be compared.

Time frame
March 2023 to December 2023

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

WGEKHALEEL

Collaborator

AARMHUSSIEN

Collaborator