High-Intensity Interval Versus Moderate-Intensity Continuous Water Based Exercise in Hypertensive Older Individuals

ConditionHypertension
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorUniversidade Estadual Paulista Júlio de Mesquita Filho

About this trial

This study will investigate the acute and chronic effects in hemodynamic and autonomic variables to high-intensity interval versus moderate-intensity continuous heated water-based exercise in older individuals with hypertension.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

≥60 years old;

Hypertension diagnosed at least 6 months earlier (stage 1 or 2);

Antihypertensive drug treatment and without dosage alteration at least 3 months earlier;

Blood pressure inferior to 140/90 mmHg in medical office.

Disqualifiers

Non 100% participation;

Change (or stopped) clinical or drug treatment.

Trial design

Design model

Parallel

Treatments tested in this trial

  • High Intensity Interval Exercise in Heated Water-Based

    Other intervention

    High intensity interval exercise will perform at controlled heated water-base (30 e 32 ºC). Subject will be submerged at the xiphoid process level. The session will consist in 4 min walking (warm-up) at 9 level of rate perceived exertion (RPE) scale, followed by 21 min of HIIE, alternating 1 min of jogging/running at 15-17 (hard-very hard) level with 2 min of walking at 9-11 (very light-fairly light) level of RPE.

  • Continuous Moderate Exercise in Heated Water-Based

    Other intervention

    Continuous moderate exercise will perform at controlled heated water-base (30 e 32 ºC). Subject will be submerged at the xiphoid process level. The session will consist in 4 min walking (warm-up) at 9 level (light) of RPE, followed by 26 min of MICE, walking at 11-13 (fairly light)level of RPE.

  • Control Group

    Other intervention

    CON session will perform at controlled heated water-base (30 e 32 ºC). Subject will be seated in a chair and submerged at the until xiphoid process level for 30 min.

Treatment groups

60 Participants
are divided into 3 treatment groups
Group A: Control without exercise in heated water-basedPlacebo comparator 1 intervention
Group B: High Intensity Interval Exercise in Heated WaterExperimental treatment 1 intervention
Group C: Continuous Moderate Exercise in Heated WaterExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Change from baseline Blood Pressure (Systolic and Diastolic) following 12 weeks of exercise.

Blood pressure will be assessed in resting (Omron HEM 7200®, Omron Healthcare Inc, Dalian, China) at the day of the sessions and using a 24 hour ambulatory blood pressure monitoring (Cardio-Mapa ®, Cardios System Ltda, Sao Paulo, Brazil), at the baseline and after 12 weeks of exercise.

Time frame
12 weeks

Secondary outcomes

1

Effect of exercise in hemodynamic and autonomic variables assessed by endothelial function, arterial stiffness and heart rate variability

The arterial stiffness will be assessed by pulse wave velocity (Vicorder®, SMT Medical GmbH \& Co., Wuerzburg, Germany) as well the endothelial function by Endocheck®. The heart rate variability will be measure using (Polar RS800CX®,Polar Electro Oy, Kempele, Finland) and 24 hour HOLTER monitoring (Cardio-Mapa ®, Cardios System Ltda, Sao Paulo, Brazil). All the measurements will be assessed at the pre and post moments of exercise protocol.

Time frame
12 weeks
2

Effect of exercise in functional capacity assessed by handgrip strength test.

The handgrip strength test will assessed using Jamar®. The purpose of this test is to measure the maximum isometric strength of the hand and forearm muscles. The participant will squeeze the dynamometer with maximum isometric effort, which is maintained for about 5 seconds.The test will be performed in a single day (pre and post 12 weeks of exercise).

Time frame
12 weeks
3

Effect of exercise in functional capacity assessed by 5 times sit to stand test.

The 5 times sit to stand test will measure the time taken to perform 5 repetitions of rising from a standard chair without armrest (seat height of 46 cm) to a full upright position as quickly as possible and without assistance. The test will be performed in a single day (pre and post 12 weeks of exercise), following the sequence described below, and with a 3-minute rest interval between them.

Time frame
12 weeks
4

Effect of exercise in functional capacity assessed by sit and reach test.

The sit and reach test (Wells®) will be used to assess the posterior thigh and lower back flexibility. The test will be performed in a single day (pre and post 12 weeks of exercise), following the sequence described below, and with a 3-minute rest interval between them.

Time frame
12 weeks

Other outcomes

Sponsors and contacts

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Universidade Estadual Paulista Júlio de Mesquita Filho

Lead sponsor

Fundação de Amparo à Pesquisa do Estado de São Paulo

Collaborator