HIIT Effects on Cardiometabolic Health
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-25
SponsorSyracuse University
About this trial
The primary aim of this randomized clinical trial is to compare the effects of three different HIIT protocols and a control group on cardiometabolic health in young adults with obesity. Participants will be randomly assigned to one of the following three groups, with each having varying work-to-rest ratios: 1) HIIT-A, 2) HIIT-B, 3) HIIT-C, and 4) control group. HIIT-A, HIIT-B, and HIIT-C groups will participate in six sessions of a running based HIIT program over a 2-week training period. Pre-clinical markers of cardiovascular disease, blood lipids and fasting glucose will be measured at the following three time points: baseline, post-intervention, and 2 weeks after the training cessation (i.e., measure for detraining effect). All measurements will be performed three days before the training program and three days after the intervention to avoid the effect of the last training session. Afterwards, the detraining test will be measured 2 weeks post intervention.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Young adults with obesity (Age 18 to 25 years old, BMI ≥ 30 kg/m2).
Disqualifiers
Syndromic obesity; 1) Any clinical symptoms including cognitive delay, 2) abnormalities in body structure(s), 3) organ-specific abnormalities (kidney, liver failure, excessive eating, and/or other signs of hypothalamic dysfunction such as fatigue, weakness and/or lack of interest in activities.
Taking weight loss medication(s)
Currently enrolled (or within previous 6 months) in a weight loss program;
An underlying disease/medications (steroids, second generation psychotropic agents, hormonal contraception, statins, antihypertensive and antidiabetic medications) that could influence carbohydrate or lipid metabolism.
Trial design
Design model
Parallel
Treatments tested in this trial
high-intensity interval training intervention
Other interventionIntervention groups include 3 arms with 3 different HIIT protocols to identify optimal exercise regimen for improving cardiometabolic health in young adults with obesity.
Treatment groups
60 Participants
are divided into 4 treatment groupsGroup A: 5s HIITExperimental treatment 1 intervention
Group B: 10s HIITExperimental treatment 1 intervention
Group C: 20s HIITExperimental treatment 1 intervention
Group D: ControlExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Height
Height (cm)
Time frame
Baseline2
Weight
Weight (kg); Change from Baseline weight at 2 week and 4 week
Time frame
Baseline, post test (2 weeks of intervention), training cessation (2 weeks of detraining)3
Body mass index
Body mass index (kg/m2); Change from Baseline BMI at 2 week and 4 week
Time frame
Baseline, post test (2 weeks of intervention), training cessation (2 weeks of detraining)4
Percentage body fat
Percentage body fat (kg); Change from Baseline percentage body fat at 2 week and 4 week
Time frame
Baseline, post test (2 weeks of intervention), training cessation (2 weeks of detraining)Sponsors and contacts
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Source ClinicalTrials.gov