Holistic Acupuncture for Patients With Chemotherapy Induced Nausea

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorVejle Hospital

About this trial

The study explores whether acupuncture as a supplement to conventional antiemetic medicine is superior in reducing the level of chemotherapy induced nausea compared to conventional anitemetic medicine alone.

A total of 90 patients experiencing chemotherapy induced nausea will be allocated 1:1 to either acupuncture and antiemetic medicine or antiemetic medicine alone.

The level of nausea and other cancer related symptoms will be assessed at baseline and 8 and 22 days after enrollment

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

≥ 18 years of age

Undergoing chemotherapy and experiencing nausea despite adherence to the prescribed antiemetic regimen

Understands and speaks Danish

Written and orally informed consent

Disqualifiers

Brain metastases

Performance status >2

Trial design

Design model

Crossover

Treatments tested in this trial

  • Holistic acupuncture and acupressure

    Other intervention

    The intervention consists of one holistic and individualized consultation with an oncologist trained in acupuncture, in connection with outpatient chemotherapy. The consultation follows the principles of Traditional Chinese Medicine (TCM). The theoretical framework applied is Zang-Fu, which describes organ imbalances and aligns closely with Western medical understanding. Based on individual assessment and anamnesis, the patient receives acupuncture combined with acupressure. A maximum of 10 needles will be used, regardless of whether a deficiency or excess condition is identified. The acupuncture needles used are CAIR Super Silicon CSC-1, size 0.20 × 25 mm. The needles are inserted perpendicularly, except for Yin Tang, which is inserted transversely. The needles will remain in place for 25 minutes.

  • Standard medical treatment

    Other intervention

    Standard treatment and care includes chemotherapy, supportive antiemetic medication, close monitoring, and management of the patient's symptoms, side effects, and overall health.

Treatment groups

90 Participants
are divided into 2 treatment groups
Group A: Holistic acupuncture and acupressureExperimental treatment 1 intervention
Group B: Standard careActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Patient reported nausea assessed on the EORTC-15-PAL Scale

Time frame
8 days after enrollment

Secondary outcomes

1

Patient reported symptom intensity according to the EORTC-15 PAL Scale

Time frame
8 and 22 days after enrollment

Other outcomes

1

Patient reported use of antiemetic medicine

Time frame
8 and 22 days after enrollment

Sponsors and contacts

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