About this trial
The investigators are investigating whether home-based tDCS over the course of four weeks can improve ADHD symptom severity and improve dysexecutive functioning (cognitive control). Further, the investigators are investigating whether there is a dose-dependent response to tDCS.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Male and female outpatients 18-65 years of age
A diagnosis of ADD/ADHD or meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.
Disqualifiers
Contraindication to tDCS: history or epilepsy, metallic implants in the head and neck, brain stimulators, vagus nerve stimulators, VP shunt, pacemakers, pregnancy.
Active substance dependence (except for tobacco).
Pregnant or nursing females.
Inability to participate in testing procedures.
Trial design
Parallel
Treatments tested in this trial
2 mA transcranial direct current stimulation (tDCS)
DevicetDCS is a non-invasive neuromodulatory technique that has previously demonstrated the ability to transiently modulate cognitive domains in both healthy and psychiatric populations. In the 2mA condition, the investigators will assist the administration of a 2mA current stimulation from the device.
1 mA transcranial direct current stimulation (tDCS)
DevicetDCS is a non-invasive neuromodulatory technique that has previously demonstrated the ability to transiently modulate cognitive domains in both healthy and psychiatric populations. In the 1mA condition, the investigators will assist the administration of a 1mA current stimulation from the device.
Sham transcranial direct current stimulation (tDCS)
DevicetDCS is a non-invasive neuromodulatory technique that has previously demonstrated the ability to transiently modulate cognitive domains in both healthy and psychiatric populations. In the sham condition, the investigators will assist the administration of a sham stimulation from the device.
Treatment groups
Trial outcomes
Primary outcomes
P300 Amplitude during Erickson Flanker Task
P300, an electrophysiological feature theorized to represent executive functioning, has been previously shown to be notably diminished during the Erickson Flanker Task (EFT) . We will be administering this task to assess changes in P300 during the EFT, and if any changes are related to subjects' assigned condition.
Global Assessment of Functioning (GAF) Scale
investigators will use GAF scale to assess the potential feasibility of at-home tDCS for future research.
Adult ADHD Self-Report Scale
Investigators will assess changes to these questionnaires in reference to assigned stimulation group to assess changes to ADHD symptomatology across study duration.
Sponsors and contacts
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