Hop Compounds on the Immune System (VH)

ConditionInflammatory Response

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-70

SponsorUniversity of Vienna

About this trial

The aim of the present study is to determine the effect of Iso-alpha-Acids and Xanthohumol from hops on the immune response of healthy participants over a timeframe of 6 hours.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

healthy

BMI: >18,5 kg/m² or <30 kg/m²

Disqualifiers

food intolerances

food allergies

chronic inflammatory diseases

metabolic diseases

Trial design

Design model

Crossover

Treatments tested in this trial

Xanthohumol
Dietary supplement
Participants receive a study drink supplemented with Xanthohumol (0 mg = Placebo, 0,125 mg, 0,375 mg or 0,75 mg soluble Xanthohumol)
Iso-alpha-Acids
Dietary supplement
Participants receive a study drink supplemented with Iso-alpha-Acids (0 mg = Placebo, 15 mg, 45 mg or 90 mg Iso-alpha-Acids)
Xanthohumol + Iso-alpha-Acids
Dietary supplement
Participants receive a study drink supplemented with Xanthohumol + Iso-alpha-Acids (0 mg = Placebo, 0,125 mg + 15 mg , 0,375 mg + 45 mg or 0,75 mg + 90 mg soluble Xanthohumol + Iso-alpha-Acids)

Treatment groups

14 Participants

are divided into 3 treatment groups

Group A: XanthohumolExperimental treatment 1 intervention

Group B: Iso-alpha-AcidsExperimental treatment 1 intervention

Group C: Xanthohumol/Iso-alpha-AcidsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Changes in parameters of immune response

Changes in concentration of interleukin 6 (ng/ml) in cell culture supernatant of stimulated cells.

Time frame

6 hours

Changes in parameters of immune response

Changes in concentration of interleukin 1 beta (ng/ml) in cell culture supernatant of stimulated cells.

Time frame

6 hours

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Vienna

Lead sponsor

Source ClinicalTrials.gov

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