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Housing, Environment, And Living Conditions for Transformed Health

ConditionsLung DiseasesChronic Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-89
SponsorUniversity of Alabama at Birmingham

About this trial

This project will compare the health effects of public housing renovation, neighborhood built and social environment improvements, and indoor air purification, alone and in combination, as well as the cost effectiveness of each approach.

STUDY 1: The study will assess the effects of public housing and neighborhood environment (built and social) improvements on health-related behaviors, psychosocial and physiologic stress, and self-reported and physiological markers of lung health and chronic disease.

STUDY 2: The study will determine whether indoor air purification can positively impact lung health in public housing sites not undergoing housing renovation, comparing a site near industrial pollution vs one less contaminated.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults age 18 years and older

English speaking

Residents of one of 4 public housing site in Birmingham, Alabama

Disqualifiers

Individuals who are not 18 years or older

Do not speak English

Do not meet the residency criteria

Trial design

Design model

Parallel

Treatments tested in this trial

  • Indoor Air Purification

    Other intervention

    An indoor air purifier with a dual HEPA/activated carbon filter, a usage tracker, and an indoor air quality monitor will be installed in public housing residences.

  • Neighborhood Improvements

    Other intervention

    Improved built environment (green space, sidewalks, street lights) and social environment (educational and workforce development programs, wrap-around social services, Internet access).

  • Housing Improvements

    Other intervention

    High-quality public housing

Treatment groups

460 Participants
are divided into 4 treatment groups
Group A: Elyton Village CommunityActive comparator 2 interventions
Group B: Southtown Court CommunityActive comparator 1 intervention
Group C: Smithfield Court CommunityActive comparator 2 interventions
Group D: Collegeville CommunityActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Change in Patient-Reported Outcomes Measurement Information System (PROMIS-10) Global Health

A self-reported measure of physical, mental, and social health. 10 item questionnaire T-score metric from zero to 100 where higher T-scores indicate better health.

Time frame
Baseline, 12 months, 24 months
2

Change in Allostatic load

Measure of cumulative stress burden as the number of 10 indicators above a threshold: (1) serum albumin \<3.8 g/dL, (2) C Reactive Protein (CRP) \>3 mg/L, (3) High-Density Lipoprotein (HDL) \<40 mg/dL, (4) total cholesterol ≥240 mg/dL, (5) heart rate ≥90 beats/min, (6) systolic Blood Pressure (BP) ≥140 mmHg, (7) diastolic BP ≥90 mmHg, (8) serum creatinine ≥1.3 mg/dL, (9) Blood Urea Nitrogen (BUN) ≥18 mg/dL, and (10) waist circumference \>88 cm in women, \>102 cm in men.

Time frame
Baseline, 12 months
3

Change in Indoor Air Quality

Particulate matter (PM2.5). Measures particles in the air that are 2.5 micrometers or smaller in diameter.

Time frame
Baseline, 6 months, 12 months (Study 2 only)

Secondary outcomes

1

The percentage change in FEV1/FVC

FEV1/FVC. A measure of lung funtion that compares the amount of air exhaled in the first second (FEV1) to the total amount of air exhaled in a forced breath (FVC).

Time frame
Baseline, 6 months, 12 months (Study 2 only)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Alabama at Birmingham

Lead sponsor

National Institute of Nursing Research (NINR)

Collaborator

Source ClinicalTrials.gov
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