About this trial
There are two objectives for this clinical trial. The first is to test whether, with the current logistics and study setup it is possible to perform the study well and see where there might be bottlenecks we couldn't predict. The second objective is to investigate the relation between the composition of the microorganisms in the soil, the crops that grow in that soil, and the human gut. During the study participants will drink three vegetable smoothies a day, for two periods of one week. The only difference between the two periods is whether the vegetables come from a farm with a low diversity of microorganisms in the soil or a high diversity. Participants will be asked to give blood samples and turn in fecal samples before and after each period.
Eligibility criteria
Qualifiers
Aged 18 to 70 years
Written informed consent
Inhabitant of Leiden
Disqualifiers
Any documented causes of chronic disease
Suspicion of or present excessive alcohol use defined as >2 units/day (>14/week)
Recent use (<3 months) of antibiotics
Any known food allergy or restriction, or following a vegan/vegetarian diet
Trial design
Treatments tested in this trial
- Low diversity vegetable smoothie
- High diversity vegetable smoothie
Treatment groups
Sponsors and collaborators
Leiden University Medical Center
Lead sponsor
Maastricht University
Collaborator