How Simplified Language Affects Comprehension and Learning in Young Autistic Children

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-4
SponsorMichigan State University

About this trial

The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with ASD. The overall objective is to determine how single-word and telegraphic simplification affects real-time language processing and word learning in young children with ASD (relative to full, grammatical utterances). The proposed project will investigate three specific aims: 1) Determine how single-word and telegraphic simplification affects language processing. 2) Determine how single-word and telegraphic simplification affects word learning. 3) Evaluate child characteristics that may moderate the effects of linguistic simplification on language processing and word learning. Aim 1 will test the hypothesis that children with ASD will process full, grammatical utterances faster and more accurately than single-word or telegraphic utterances. Aim 2 will test the hypothesis that full, grammatical utterances will support word learning better than telegraphic or single-word utterances. Aim 3 will test the hypothesis that language and cognitive skills significantly moderate the effects of linguistic simplification on language processing and word learning in young children with ASD.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Existing or suspected autism spectrum disorder, confirmed through ADOS-2

English as primary language

1-4 years old

Disqualifiers

Known genetic condition (e.g., Down syndrome, fragile X)

Cerebral palsy

Acquired brain injury

Uncorrected vision or hearing impairment

Trial design

Design model

Single group

Treatments tested in this trial

  • Linguistic simplification

    Behavioral

    Children will participate in screen-based language processing and word learning tasks in which they hear utterances with different types and amounts of linguistic simplification (i.e., a within-group manipulation).

Treatment groups

104 Participants
are divided into 1 treatment group
Group A: Utterance TypeExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Gaze location on Looking-While-Listening (LWL) tasks

LWL involves a child looking at a screen with two images, one on each side of the screen, while being provided an auditory cue that includes the name of the target image. The primary outcome is a dichotomous variable indicating whether the child is fixated on the target image or the distracter image; gaze directed at neither image will be considered missing. It will be determined whether gaze is to the left or right image, using trained coders who are blind to target side. Gaze location will be observed every 33 ms from 300 ms after onset to 2000 ms after target word onset, for a total of 51 observations per trial. Analyses will focus on differences across trial types and child characteristics in the trajectory of gaze location over the course of the trial.

Time frame
Single assessment per task; total duration less than 10 minutes per task

Secondary outcomes

1

Gaze location in Teaching Phase of Study 2b (Fast Mapping)

A secondary outcome measure will be gaze location during the Teaching Phase of the Fast Mapping task (Study 2b). The variable is a dichotomous variable indicating whether the child is fixated on the novel image (only a single image is presented in each trial during the Teaching Phase) or not. It will be determined whether gaze is directed to the novel image, as our prior attempts to manually code single-object trials have not been successful. Only children who successfully calibrate and provide adequate automatic eye-tracking data in the Fast Mapping task will be included. Gaze location will be observed every 33 ms during the Teaching Trials. Analyses will focus on differences across trial types (single-word vs. full, grammatical teaching utterances).

Time frame
Single assessment; total duration less than 10 minutes

Other outcomes

Sponsors and contacts

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Michigan State University

Lead sponsor

National Institute on Deafness and Other Communication Disorders (NIDCD)

Collaborator