HS ABSCESSES: I&D VS PUNCH DEBRIDEMENT

ConditionHidradenitis Suppurativa (Acne Inversa)

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age16+

SponsorErasmus Medical Center

About this trial

This randomized-control trial is designed to determine the recurrence rate of HS abscesses following drainage via two methods: I\&D with a linear incision and PD with an 8mm punch biopsy. In this context, recurrence is a newly described HS abscess adjacent to or within the previously operated area, for which a second intervention is deemed necessary. We hypothesize that PD may yield a more favorable recurrence rate. In addition to comparing recurrence rates, this randomized-control trial will also evaluate postprocedural pain, the occurrence and type of complications, and patients' quality of life associated with both procedures. These additional factors are crucial in assessing the overall effectiveness and patient satisfaction associated with each method, further informing the potential establishment of PD as the new gold standard for draining small, painful, acute HS abscesses.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Diagnosed with HS

Has an abscess requiring drainage with a maximum diameter of 5 centimeters.

Age 16 years or older

Willing and able to provide informed consent

Disqualifiers

Has other conditions that could interfere with the study, as estimated by physician

Unable to comply with follow-up visits

Allergic to lidocaine and/or adrenaline.

Trial design

Design model

Parallel

Treatments tested in this trial

Punch Debridement
Procedure/Surgery
A punch biopsy tool is positioned over the inflamed follicular unit, and a small circle of skin (4 to 8 mm in diameter) is excised. A firm twisting motion is necessary to ensure adequately deep excision.
Incision and Drainage
Procedure/Surgery
Incision and Drainage is a minimally invasive surgical procedure often employed for the treatment of intensely painful, tense, and fluctuant abscesses that are too deep to drain spontaneously. After administration of a broad circumferential local anesthetic, a small linear incision is made using a standard scalpel blade. Digital pressure is applied to expel the fluid collection. Saline rinses can be used to flush out the remaining contents. This method offers instant pain relief, commonly performed in acute settings by dermatologists, emergency department physicians and general practitioners

Treatment groups

72 Participants

are divided into 2 treatment groups

Group A: Punch DebdridementExperimental treatment 1 intervention

Group B: Gold standard: Incision and DrainageActive comparator 1 intervention

Trial outcomes

Primary outcomes

Recurrence

Recurrence rate in percentage of abscesses recurring after drainage

Time frame

1 month

Sponsors and contacts

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Erasmus Medical Center

Lead sponsor

Source ClinicalTrials.gov

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