Human Microbiome Research and Development for Overcoming Pediatric Diseases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorHanyang University
About this trial
Prediction and treatment of pediatric diseases and long-term outcomes through microbiome and multi-omics analysis by life cycle: We aim to demonstrate that a wide range of diseases are associated with gut microbiome dysbiosis and to investigate the subsequent recovery (restoration) or further deterioration of the gut microbiome over time. This study seeks to offer a novel perspective on changes in the gut microbiome, particularly in the context of the gut-lung and gut-brain axes.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
children (including newborns) who have obtained their consent from their guardians
Disqualifiers
subjects who did not obtain consent
Trial population
Control group: healthy infants without any diagnosed diseases, born full-term, exhibiting normal growth and development. Case group: infants with diagnosed diseases, including those born prematurely, those with a history of neonatal intensive care unit (NICU) admission, and those exhibiting neurodevelopmental impairments.
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Follow-up of growth percentile in height, weight, and head circumference
Monitoring the baby's growth status compared to the Nomogram growth chart
Time frame
2 months old, 4 months old, 6 months old, 1 year old, and then every year until the age of ten years2
Obervation of age-specific developmental milestones
Judging whether the development status is appropriate according to developmental milestones based on developmental screening tests and doctors' opinions)
Time frame
4 months old, 1 year old, 3 years old, school age3
Observations on the incidence and frequency of enteritis, sepsis, and respiratory diseases
The dysbiosis of the gut microbiome affects various organs, such as the gut-lung axis and the gut-brain axis, in addition to the disease of the intestine itself, so monitor the occurrence of infectious diseases
Time frame
2 months old, 4 months old, 6 months old, 1 year old, and then every year until the age of ten yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov