About this trial
The goal of this clinical trial is to learn if an interactive mHealth intervention will be effective in helping HIV-positive women in high-burden settings who are initiating antiretroviral therapy (ART) take their ART regularly as prescribed, effectively reducing their viral load. The main question it aims to answer is:
\- Compared to standard of care, will Motivation Matters! (MM!) be significantly more effective at achieving undetectable viral load in women with HIV by month six.
Researchers will compare the undetectable HIV viral load in women who receive individualized text messages (intervention group) in addition to standard care to those who receive standard care alone (control group).
Participants in the intervention group will receive three messages per week in month one, then two messages per week for the six-month intervention period. Participants will be asked to send a brief, standardized reply to each message, indicating that they are doing well or that they have a question or problem. Regardless of study arm, women will receive ART and counseling consistent with Kenyan guidelines.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age >18
Transactional sex in past 12 months
HIV-positive
Not currently on ART
Disqualifiers
Plans to move away in next 6 months
Undetectable viral load at baseline
Pregnant
Trial design
Parallel
Treatments tested in this trial
Text message mHealth Evidence-based intervention
BehavioralMM! includes three messages per week in month one, then two messages per week for the six-month intervention period. Earlier messages include more informational and motivational content, while later messages include more behavioral skills.
Treatment groups
Trial outcomes
Primary outcomes
Participants with undetectable viral load at 6 months
Sponsors and contacts
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University of Washington
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
Partners for Health and Development in Africa (PHDA)
Collaborator