Health TrialsbyHealthPanel

Hyperspectral Imaging in Robot-Assisted Partial Nephrectomy

ConditionsKidney NeoplasmRenal Mass up to 7cm
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Leipzig

About this trial

The goal of this prospective observational study is to learn about the use of a novel imaging technique called hyperspectral imaging in adult participants who are having surgery for removing a tumor from their kidney. Hyperspectral imaging works by shining light on a structure (in this case, the kidney tissue with the tumor) and capturing how it reflects hundreds of very narrow color bands, including ones the human eye can't see. These patterns depend on the composition of the tissue and for example how well blood is flowing through the tissue. By studying these patterns, the investigators want to understand if this technique can be helpful for the surgery where only the part of the kidney with the tumor is removed.

The main questions it aims to answer are:

* Can hyperspectral imaging show the areas of blood flow in the kidney during surgery? * Is there a connection between the detected patterns of light and the type of kidney tumor?

The imaging will happen during the already planned surgery and the participant does not need to undergo any additional tests.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with a kidney tumor ≤7cm

planned robot-assisted partial nephrectomy

age ≥ 18 years

Disqualifiers

patients with a previous surgery on the affected kidney

patients with a fully intrarenal/endophytic tumor without an exophytic component

previous malignancy with ongoing or planned nephrotoxic chemotherapy

current immunosuppression (e.g., organ transplantation, leukemia)

Trial population

Eligible participants for the trial will be selected from all patients referred to the Department of Urology at the University Hospital Leipzig for undergoing partial nephrectomy.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Correlation of hyperspectral imaging (HSI) data with clamping technique during robot-assisted partial nephrectomy (RAPN)

Time frame
day of surgery
2

Correlation of HSI data with histopathological report

Time frame
day of surgery

Secondary outcomes

1

Correlation of HSI data with demographic parameters

Time frame
day of surgery
2

Correlation of HSI data and respective clamping technique with postoperative kidney function

Time frame
from the day of surgery until discharge (up to 6 days)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Leipzig

Lead sponsor

Source ClinicalTrials.gov
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