ICU patients are recruited after at least 5 days treatment with continuous renal replacement therapy. Blood samples are drawn at time of recruitment and then every 3-5 days until ceseation of renal replacement therapy.
Samples will be analyzed for concentrations of trace elements, vitamins and amino acids.
10 adult ICU patients treated for two weeks without renal replacement therapy will be sampled at one time point to serve as controls.
CRRT more than 5 days
N/A
Patient of all ages treated with CRRT
Other
Prospective
blood test
Diagnostic testBlood samples are drawn every 3-5 days in the RRT group but only once in the control group
Concentration of trace element
Measurments of trace elements and vitamins as compared to established reference values as well as non-CRRT controls
Amino acids
Concentration of amino acids in plasma
Vitamins
Water soluble vitamins, concentration in plasma. Compared to non-crrt controls and established references
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