About this trial
Intersegmental plane identification is a critical step in thoracoscopic anatomical segmentectomy because it helps ensure adequate surgical margins while preserving healthy lung tissue. Indocyanine green (ICG) fluorescence imaging and carbon dioxide (CO₂) inflation-deflation are two techniques used to identify the intersegmental plane, but their agreement and clinical applicability have not been adequately evaluated.
This prospective paired study aims to compare the intersegmental planes identified by ICG fluorescence imaging and the CO₂ inflation-deflation method during thoracoscopic anatomical segmentectomy. In each participant, both techniques will be performed during the same operation, and the identified intersegmental planes will be compared. The findings of this study may provide evidence regarding the agreement and clinical applicability of the two methods for intersegmental plane identification.
Eligibility criteria
Qualifiers
Adults aged 18 to 80 years.
Scheduled to undergo elective thoracoscopic anatomical segmentectomy.
Preoperative thin-section chest CT with three-dimensional reconstruction available for surgical planning.
Lesion considered suitable for anatomical segmentectomy by the thoracic surgery team.
Disqualifiers
Known allergy or contraindication to indocyanine green (ICG).
Pregnant or breastfeeding women.
Severe hepatic dysfunction or other conditions contraindicating the use of ICG.
Severe emphysema, bullous lung disease, diffuse pulmonary fibrosis, or other severe pulmonary parenchymal disease expected to interfere with intersegmental plane identification.
Trial design
Treatments tested in this trial
- Indocyanine Green Fluorescence Imaging
- Carbon Dioxide Inflation-Deflation