Identification of Circulating Biomarkers Associated With Extracellular Vesicles in Sarcomas

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorIstituto Ortopedico Rizzoli

About this trial

The study involves blood samples from patients with Ewing's sarcoma to identify circulating biomarkers as a tool for the preclinical validation of innovative therapeutic approaches

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Male and female patients of any age diagnosed with Ewing sarcoma.

Signed, study-specific informed consent form for the BIOVES study (cancer patients)

Male and female patients of legal age without a cancer diagnosis.

Signed, study-specific informed consent form for the BIOVES study (non-cancer patients)

Disqualifiers

None

Trial population

The study aims to enroll patients of any gender who are being treated at the Rizzoli Orthopedic Institute in the following departments: Orthopedic and Traumatology Clinic III (with a primary focus on oncology), General and Thoracic Surgery (for both cancer and non-cancer patients), and Osteoncology, Bone and Soft Tissue Sarcomas, and Innovative Therapies (for cancer patients only).

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • one blood sample

    Other intervention

    non onco

  • 3 blood samples

    Other intervention

    onco

Treatment groups

16 Participants
are divided into 2 treatment groups
Group A: oncological subject1 intervention
Group B: non-oncological subjects1 intervention

Trial outcomes

Primary outcomes

1

characterisation of circulating biomarkers

search for circulating biomarkers from blood samples taken at three different time points

Time frame
at baseline (time 0); before surgery; after 6 months from surgery

Secondary outcomes

Other outcomes

Sponsors and contacts

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