Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorMassachusetts General Hospital
About this trial
This study is being conducted to investigate gut-brain communication in individuals with functional dyspepsia and anorexia nervosa. The hope is that what the investigators learn from this study will improve the understanding the conditions better to improve treatments.
Eligibility criteria
Qualifiers
Males and females; ages 18-65 years
Rome V functional dyspepsia post-prandial distress syndrome subtype
Negative upper endoscopy or upper GI series to rule out structural/organic cause for FD
greater than or equal to 5.5 gut interoceptive awareness score (by VSI awareness subscale)
Disqualifiers
Pyloric or intestinal obstruction (by EGD, UGI, or Abdominal CT)
Active H.pylori (by CLO test or stool antigen test)
Active inflammatory bowel disease
Eosinophilic gastroenteritis or eosinophilic esophagitis
Trial design
Treatments tested in this trial
- Functional magnetic resonance imaging (fMRI)
Treatment groups
150 Participants
are divided into 1 treatment groupSponsors and collaborators
Massachusetts General Hospital
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Source ClinicalTrials.gov