Health TrialsbyHealthPanel

Imaging-based Assessment of Oral Biofilm and Gingival Health

ConditionsPlaque, DentalGingivitis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of California, Irvine

About this trial

The purpose of this research study is to develop a better way of measuring the health of patients' mouth using photographs and imaging software. The investigators will also study the specific effects of individual toothpastes and mouthwashes on oral health.

Participants who have volunteered to be in the study will be asked to use a toothpaste or over a period of 7 days to 6 months. The investigators will determine the participants' oral plaque levels, gum health, and saliva (spit) production with clinical exams as well as photographs of the participants' mouths. It is the hope of the study team to find better ways of assessing the health of patients' mouths and to identify whether gum health can be improved by specific toothpastes or mouthwashes.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

At least 18 years of age or older

In good general health

Disqualifiers

History of allergy or intolerance of oral hygiene products such as toothpastes and mouthrinses

Trial design

Design model

Parallel

Treatments tested in this trial

  • OTC Toothpastes or Mouthrinses

    Other intervention

    OTC Toothpastes or mouthrinses used according to standard of care

Treatment groups

275 Participants
are divided into 7 treatment groups

7

Treatment groups

See each treatment group below.

Group A: Brushing with LivFresh Dental GelActive comparator 1 intervention
Group B: Brushing with LivFree Dental GelActive comparator 1 intervention
Group C: Brushing with AIM Dental GelActive comparator 1 intervention
Group D: Brushing with Crest Prohealth Dental GelActive comparator 1 intervention
Group E: Brushing with Parodontax Dental GelActive comparator 1 intervention
Group F: Brushing with Colgate Total Dental GelActive comparator 1 intervention
Group G: Rinsing with Lumineux or Listerine MouthwashesActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Plaque level at Week 1

Oral plaque will be measured using the gold standard plaque index (0-5; 0-best, 5 worst).

Time frame
1 week
2

Plaque level at Month 1

Oral plaque will be measured using the gold standard plaque index (0-5; 0-best, 5 worst).

Time frame
1 month
3

Plaque level at Month 3

Oral plaque will be measured using the gold standard plaque index (0-5; 0-best, 5 worst).

Time frame
3 months
4

Plaque level at Month 6

Oral plaque will be measured using the gold standard plaque index (0-5; 0-best, 5 worst).

Time frame
6 months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of California, Irvine

Lead sponsor

Source ClinicalTrials.gov
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