Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk
ConditionSudden Cardiac Death
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorJohns Hopkins University
About this trial
Sudden cardiac death is a tragic event that strikes all age groups and is unfortunately increasing in prevalence. Because it is difficult to predict those at highest risk, this study is designed to test the hypothesis that new imaging techniques (magnetic resonance imaging \[MRI\] and computed tomography \[CT\]) are useful for identifying factors which put people at high risk for sudden death.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Left ventricular ejection fraction <or = 35%
Planned implantable cardioverter-defibrillator (ICD) implantation for clinical indications (primary prevention)
Disqualifiers
History of sudden death (secondary prevention)
Contraindication to undergoing MRI (metallic implant, pacemaker, etc.)
Trial population
Patients with contractile dysfunction (EF\< or = 35%) on an ischemic or non-ischemic basis undergoing clinically-indicated ICD implantation for primary prevention of sudden cardiac death (SCD)
Trial design
Design model
Other
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
sudden cardiac death
Time frame
6 month intervals2
cardiovascular death
Time frame
6 month intervals3
appropriate ICD discharge
Time frame
6 month intervals4
composite sudden cardiac death and appropriate ICD discharge
Time frame
6 month intervalsSecondary outcomes
1
heart failure admission
Time frame
6 month intervalsOther outcomes
1
cardiac transplantation
Time frame
6 month intervals2
myocardial revascularization
Time frame
6 month intervals3
left ventricular assist device placement
Time frame
6 month intervals4
biventricular pacemaker placement
Time frame
6 month intervalsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Johns Hopkins University
Lead sponsor
Donald W. Reynolds Foundation
Collaborator
Source ClinicalTrials.gov