Immediate Effects of PETTLEP-Based AOMI on Upper Limb Kinematics in Stroke Survivors
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-80
SponsorIstinye University
About this trial
The purpose of this study is to investigate the immediate effects of a mental practice technique, called Physical, Environment, Task, Timing, Learning, Emotion, Perspective (PETTLEP)-based Action Observation and Motor Imagery (AOMI), on arm movement in stroke survivors. Stroke often causes difficulty in moving the arm smoothly, leading patients to compensate by using their back or shoulder. In this study, participants will either receive a single session of the AOMI training (watching and mentally practicing a reach-to-grasp movement) or a control relaxation task. The researchers will use a smartphone-based motion capture system (OpenCap) to measure if the mental practice immediately improves the smoothness of the arm movement and reduces compensatory body movements.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Female and male adults aged 40 to 80 years with a diagnosis of unilateral ischemic or hemorrhagic stroke.
Residual voluntary movement activity of the affected upper limb.
Mild to moderate spasticity (Modified Ashworth Scale ≤ 3).
Adequate cognitive function to understand and follow verbal instructions (Mini-Mental State Examination ≥ 21).
Disqualifiers
Other central nervous system disorders (e.g., Parkinson's disease, multiple sclerosis, traumatic brain injury).
Musculoskeletal or orthopedic conditions causing restriction of movement in the upper-limb (such as fixed contractures, severe joint deformities, shoulder subluxation).
Severe sensory deprivation, visual neglect, or inattention that interferes with completion of the task or the ability to engage in motor imagery.
Uncontrolled seizures, severe cardiovascular instability, or any other contraindication to imagery.
Trial design
Design model
Parallel
Treatments tested in this trial
PETTLEP-based Action Observation and Motor Imagery (AOMI)
BehavioralA mental practice protocol involving sensory priming, action observation, and motor imagery of a reach-to-grasp task with selective functional constraints (Smoothness, Dissociation/Glued Back, and Relaxed Shoulder).
Cognitive and Somatic Control Tasks
BehavioralStructured operations including somatic attention (body scanning) and visuospatial control (spatial navigation) timed and paired to exhaust attention without motor system participation.
Treatment groups
28 Participants
are divided into 2 treatment groupsGroup A: Experimental Group: PETTLEP-based AOMIExperimental treatment 1 intervention
Group B: Control Group: Cognitive and Somatic ControlSham comparator 1 intervention
Trial outcomes
Primary outcomes
1
Change in Movement Smoothness (Number of Velocity Peaks)
Movement smoothness of the affected upper limb will be evaluated using the OpenCap system (a markerless 3D motion capture system). It is calculated by the Number of Velocity Peaks (NVP) derived from the hand marker (3rd Metacarpal head) velocity profile during a standardized reach-to-grasp task. A reduction in NVP indicates increased movement smoothness and better motor control.
Time frame
Immediately before the intervention (baseline) and immediately after the single 25-minute intervention session.Secondary outcomes
1
Shoulder Girdle Elevation (Compensatory Strategy)
Calculated by measuring the relative vertical (Y axis) displacement of the Shoulder marker with respect to the Neck marker during movement using the OpenCap system.
Time frame
Immediately before and immediately after the 25-minute intervention session.2
Trunk Displacement (Compensatory Strategy)
Calculated by measuring the change in the Lumbar Extension angle in the sagittal plane during the reaching phase, obtained from the OpenSim kinematic model.
Time frame
Immediately before and immediately after the 25-minute intervention session.3
Gross Manual Dexterity - Box and Block Test (BBT)
Participants are asked to move as many blocks as they can from one side of a wooden box to the other in 60 seconds using their affected hand. The score is the number of blocks moved successfully.
Time frame
Immediately before and immediately after the 25-minute intervention session.4
Pain - Visual Analog Scale (VAS)
Participants indicate their pain intensity by placing a mark on a 10-cm horizontal line. The left side is labeled "no pain" (0) and the right side is labeled "worst pain imaginable".
Time frame
Immediately before and immediately after the 25-minute intervention session.Locations
Sponsors and contacts
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Source ClinicalTrials.gov
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