About this trial
Analysis of peripheral immune cells before, during, and after brachytherapy treatment. Corresponding analysis of tissue samples collected during brachytherapy treatment.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Primary treatment with I-125 seeds or HDR-BT
No previous treatment for prostate cancer
Age ≥ 18 years
HDR- or PDR-BT
Disqualifiers
Pre-existent auto-immune disease
patients under bloodthinning medication
substance abuse
Trial population
Prostate cancer patients planning to undergo sole brachytherapy treatment
Trial design
Other
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Longitudinal changes of peripheral immune cells and cell-free DNA and tumor-associated tissue in patients with prostate cancer treated with brachytherapy
Longitudinal changes of peripheral immune cells and cell-free DNA and tumor-associated tissue in patients with prostate cancer treated with brachytherapy in the primary as well as in the recurrent setting.
Secondary outcomes
Treatment-related toxicity
Acute toxicity related to brachytherapy
recurrence-free survival
recurrence-free survival
Overall survival
Overall survival
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Erlangen-Nürnberg Medical School
Lead sponsor
Bavarian Cancer Research Center (BZKF)
Collaborator
University Hospital Augsburg
Collaborator
Ludwig-Maximilians - University of Munich
Collaborator