Immunity With Acute Hepatits A
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-15
SponsorAssiut University
About this trial
Hepatitis A Virus (HAV) is a public health concern in Egypt, especially among children. Historically highly endemic, recent studies suggest a changing epidemiology. While improved socioeconomic conditions have reduced its spread, HAV remains prevalent, with over 50% of Egyptians exposed by age 15. Infection is often asymptomatic or mild in children but can be more severe with age. Prevention relies on improved sanitation and hygiene, with vaccin and recov
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Children aged 1-15 years
Confirmed diagnosis of acute hepatitis A infection (positive anti-HAV IgM)
Admitted to the hospital for management of acute hepatitis A
Parental/guardian consent and child assent (where appropriate) obtained
Disqualifiers
Known pre-existing liver disease or chronic hepatitis
Immunodeficiency disorders or current immunosuppressive therapy
Coinfection with other hepatotropic viruses (HBV, HCV, HEV)
Severe malnutrition
Trial population
Children aged 1-15 years
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Correlation between lymphocyte subset levels and development of hepatic encephalopathy or fulminant hepatic failure
Time frame
One yearLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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