Impact of 3D-EIT-Guided Acapella Breathing Training on Lung Ventilation Distribution
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorShanghai Zhongshan Hospital
About this trial
The goal of this randomized clinical trial is to determine whether real-time visual feedback from three-dimensional electrical impedance tomography (3D-EIT) can improve the effects of Acapella breathing exercises in adults recovering from critical illness. 3D-EIT is a noninvasive bedside imaging method that provides real-time information about how ventilation is distributed within the lungs.
Participants will be randomly assigned to one of two groups. Both groups will perform a standardized Acapella breathing exercise while 3D-EIT data and vital signs are recorded. Participants in the control group will receive routine verbal and demonstration-based breathing instructions without viewing the EIT images. Participants in the intervention group will receive the same instructions and will also view their own real-time 3D-EIT ventilation images. They will use this visual feedback to adjust their breathing with the goal of increasing ventilation in the dorsal regions of the lungs and/or achieving a more even distribution of ventilation.
The main question is whether 3D-EIT-guided visual feedback results in a greater improvement in end-expiratory lung impedance (EELI) after breathing exercise compared with routine instruction alone. The study will also examine changes in regional ventilation distribution, ventilation inhomogeneity, vital signs, breathing discomfort, comfort and tolerance, achievement of the breathing-training target, and adverse events.
Approximately 30 participants will be enrolled and randomly assigned in a 1:1 ratio to the two study groups.
Eligibility criteria
Qualifiers
Age ≥18 years.
Adult patients in the stable recovery phase following critical illness, breathing spontaneously, alert, and able to follow instructions (suggested Richmond Agitation-Sedation Scale [RASS] score of -1 to +1).
Hemodynamically stable, with no vasopressor support or only a low and stable dose of vasopressors.
Receiving stable low-flow oxygen therapy or equivalent non-escalating respiratory support, without an anticipated need for escalation in the short term.
Disqualifiers
Significant hemodynamic instability or clinically significant cardiac arrhythmia.
Untreated pneumothorax or active hemoptysis.
Severe chest wall skin injury or allergy to electrode materials that prevents application of the electrical impedance tomography electrodes.
Significant delirium or inability to understand or follow study instructions.
Trial design
Treatments tested in this trial
- Acapella Oscillating Positive Expiratory Pressure Breathing Exercise
- Real-Time 3D Electrical Impedance Tomography Visual Biofeedback
Treatment groups
30 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov